Research
Studies
We rely on volunteers for many of our research projects. If you would like to support our research and take part in a study, you will find further information and contact details in the links provided.
ACRODAT - Prospective evaluation of the ACRODAT app in everyday clinical practice
When acromegaly is diagnosed, it is standard practice to ask about the patient's clinical condition and to monitor autonomous growth hormone secretion by measuring the IGF-1 level in order to record the activity of the disease. In our research project, we want to find out whether the use of ACRODAT, a newly developed medical software, can lead to better therapy results. This software systematically links symptoms, laboratory findings and imaging findings to provide a better and more complete picture of disease activity, which will hopefully lead to better treatment outcomes.
Contact
Prof. Emanuel Christ
Head of Interdisciplinary Endocrinology
Tel. (24h availability): +41 79 524 48 71
emanuel.christ@usb.ch
Link:https://www.kofam.ch/de/studienportal/nach-klinischen-versuchen-suchen/172828/studie/59526
EMPOWER - Effect of the SGLT2 inhibitor empagliflozin on patients with euvolemic and hypervolemic hyponatremia
This study is aimed at adult hospitalized patients who suffer from low blood sodium levels (= hyponatremia).
The study investigates the effects of the drug empagliflozin (Jardiance)® on the sodium levels of patients who chronically suffer from low blood sodium levels due to the syndrome of inadequate antidiuresis (SIAD), heart failure, impaired liver or kidney function. We are conducting this study to investigate the efficacy and tolerability of this new therapy.
Contact
Dr. Sophie Monnerat
Phone +41 61 328 76 08
sophie.monnerat@usb.ch
Link: https://www.kofam.ch/de/studienportal/nach-klinischen-versuchen-suchen/studie/53049
Acute consequences of glucocorticoid secretion in overweight individuals during maximal caloric intake - The Gluco-Max study
We are investigating the consequences of the release of cortisol (stress hormone) on weight regulation after eating.
We are looking for: Overweight men between the ages of 18 and 50 without serious illnesses such as type 2 diabetes mellitus.
Link: https://clinicaltrials.gov/study/NCT06556277?term=gluco%20max&rank=1
Contact
Dr. med. univ. Jil Claire Chevailler
Tel. 061 328 48 41
PROPHECY - Role of prostaglandins in the prediction of low salt levels under thiazide therapy
This study is aimed at adult outpatients and hospitalized patients who are newly prescribed a thiazide or thiazide-like diuretic.
Thiazide and thiazide-like diuretics are diuretic drugs (so-called "water tablets"). A common side effect of thiazide diuretics is a lowered salt level in the blood. There is currently no known screening test to detect an increased risk of this side effect before the start of therapy. In our research project, we therefore want to find out whether the determination of the prostaglandin E2 concentration in the urine (tissue hormone) before the start of therapy can predict the occurrence of a low salt level in the blood.
Contact
Dr. Julia Beck
julia.beck@usb.ch
THAP study - In this study, we are investigating various methods for neck vein ultrasound to assess body water - for their accuracy and normal values in healthy patients.
In this study, we are investigating various methods for neck vein ultrasound to assess body water - in terms of their accuracy and normal values in healthy patients.
We are looking for:
Adult patients
- Without known heart / kidney problems or diabetes
- Without blood pressure medication or diuretics ("water tablets")
Contact:
Dr. med. sc. Laura Potasso,
Tel 061 328 58 76
THAT Study - New blood and urine markers for simple therapy decisions in patients with thiazide diuretics and low salt in the blood (=hyponatremia) - THAT Study
In this study, we are investigating new blood and urine markers to improve the diagnosis and treatment of various forms of low blood salt (hyponatremia) in patients taking thiazide medication.
We are looking for:
Adult patients hospitalized at the University Hospital Basel with sodium < 130mmol/l and thiazide / thiazide-like diuretics
Link: https://kofam.ch/en/snctp-portal/searching-for-a-clinical-trial/245672/study/68787
Contact:
Dr. med. sc. Laura Potasso,
Tel. 061 328 58 76